Results: 72 1.Xanthohumol activates the proapoptotic arm of the unfolded protein response in chronic lymphocytic leukemia.

Lust S, Vanhoecke B, VAN Gele M, Boelens J, VAN Melckebeke H, Kaileh M, Vanden Berghe W, Haegeman G, Philippé J, Bracke M, Offner F.

Anticancer Res. 2009 Oct;29(10):3797-805.PMID: 19846911.Xanthohumol enhances antiviral effect of interferon alpha-2b against bovine viral diarrhea virus, a surrogate of hepatitis C virus.

Zhang N, Liu Z, Han Q, Chen J, Lv Y.

Phytomedicine. 2009 Sep 10. [Epub ahead of print]PMID: 19748253 Inhibition of bovine viral diarrhea virus in vitro by xanthohumol: comparisons with ribavirin and interferon-alpha and implications for the development of anti-hepatitis C virus agents.

Zhang N, Liu Z, Han Q, Chen J, Lou S, Qiu J, Zhang G.

Eur J Pharm Sci. 2009 Nov 5;38(4):332-40. Epub 2009 Aug 29.PMID: 19720145 Inhibition of Suicidal Erythrocyte Death by Xanthohumol.

Qadri SM, Mahmud H, Föller M, Lang F.

J Agric Food Chem. 2009 Jul 30. [Epub ahead of print]PMID: 19642672 Xanthohumol from Hop ( Humulus lupulus L.) Is an Efficient Inhibitor of Monocyte Chemoattractant Protein-1 and Tumor Necrosis Factor-alpha Release in LPS-Stimulated RAW 264.7 Mouse Macrophages and U937 Human Monocytes.

Lupinacci E, Meijerink J, Vincken JP, Gabriele B, Gruppen H, Witkamp RF.

J Agric Food Chem. 2009 Jul 27. [Epub ahead of print]PMID: 19634869 Immunomodulatory activity of xanthohumol: inhibition of T cell proliferation, cell-mediated cytotoxicity and Th1 cytokine production through suppression of NF-kappaB.

Gao X, Deeb D, Liu Y, Gautam S, Dulchavsky SA, Gautam SC.

Immunopharmacol Immunotoxicol. 2009;31(3):477-84.PMID: 19555200 Fundamentals and health benefits of xanthohumol, a natural product derived from hops and beer.

Magalhães PJ, Carvalho DO, Cruz JM, Guido LF, Barros AA.

Nat Prod Commun. 2009 May;4(5):591-610. Review.PMID: 19445313 In vitro evaluation of antibacterial, anticollagenase, and antioxidant activities of hop components (Humulus lupulus) addressing acne vulgaris.

Yamaguchi N, Satoh-Yamaguchi K, Ono M.

Phytomedicine. 2009 Apr;16(4):369-76. Epub 2009 Feb 6.PMID: 19201179 Xanthohumol influences preadipocyte differentiation: implication of antiproliferative and apoptotic effects.

Mendes V, Monteiro R, Pestana D, Teixeira D, Calhau C, Azevedo I.

J Agric Food Chem. 2008 Dec 24;56(24):11631-7.PMID: 19035642 Increased IL-2 production in T cells by xanthohumol through enhanced NF-AT and AP-1 activity.

Choi JM, Kim HJ, Lee KY, Choi HJ, Lee IS, Kang BY.

Int Immunopharmacol. 2009 Jan;9(1):103-7. Epub 2008 Nov 17.PMID: 19019318 Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells.

Harikumar KB, Kunnumakkara AB, Ahn KS, Anand P, Krishnan S, Guha S, Aggarwal BB.

Blood. 2009 Feb 26;113(9):2003-13. Epub 2008 Oct 24.PMID: 18952893 Inhibitory effects of xanthohumol from hops (Humulus lupulus L.) on human hepatocellular carcinoma cell lines.

Ho YC, Liu CH, Chen CN, Duan KJ, Lin MT.

Phytother Res. 2008 Nov;22(11):1465-8.PMID: 18814205 Antileukemia effects of xanthohumol in Bcr/Abl-transformed cells involve nuclear factor-kappaB and p53 modulation.

Monteghirfo S, Tosetti F, Ambrosini C, Stigliani S, Pozzi S, Frassoni F, Fassina G, Soverini S, Albini A, Ferrari N.

Mol Cancer Ther. 2008 Sep;7(9):2692-702.PMID: 18790751 Effect of xanthohumol on melanogenesis in B16 melanoma cells.

Koo JH, Kim HT, Yoon HY, Kwon KB, Choi IW, Jung SH, Kim HU, Park BH, Park JW.

Exp Mol Med. 2008 Jun 30;40(3):313-9.PMID: 18587269 Xanthohumol inhibits inflammatory factor production and angiogenesis in breast cancer xenografts.

Monteiro R, Calhau C, Silva AO, Pinheiro-Silva S, Guerreiro S, Gärtner F, Azevedo I, Soares R.

J Cell Biochem. 2008 Aug 1;104(5):1699-707.PMID: 18348194 Differential anti-inflammatory pathway by xanthohumol in IFN-gamma and LPS-activated macrophages.

Cho YC, Kim HJ, Kim YJ, Lee KY, Choi HJ, Lee IS, Kang BY.

Int Immunopharmacol. 2008 Apr;8(4):567-73. Epub 2008 Jan 24.PMID: 18328448 Pharmacognostic and pharmacological profile of Humulus lupulus L.

Zanoli P, Zavatti M.

J Ethnopharmacol. 2008 Mar 28;116(3):383-96. Epub 2008 Jan 20. Review.PMID: 18308492 Inhibition of topoisomerase I activity and efflux drug transporters' expression by xanthohumol. from hops.

Lee SH, Kim HJ, Lee JS, Lee IS, Kang BY.

Arch Pharm Res. 2007 Nov;30(11):1435-9.PMID: 18087812 Antigenotoxic effect of Xanthohumol in rat liver slices.

Plazar J, Filipic M, Groothuis GM.

Toxicol In Vitro. 2008 Mar;22(2):318-27. Epub 2007 Sep 25.PMID: 17981005 Antimutagenicity of hops (Humulus lupulus L.): bioassay-directed fractionation and isolation of xanthohumol.

Kac J, Plazar J, Mlinaric A, Zegura B, Lah TT, Filipic M.

Phytomedicine. 2008 Mar;15(3):216-20. Epub 2007 Oct 23.PMID: 17959367 Effect of xanthohumol and isoxanthohumol on 3T3-L1 cell apoptosis and adipogenesis.

Yang JY, Della-Fera MA, Rayalam S, Baile CA.

Apoptosis. 2007 Nov;12(11):1953-63.PMID: 17874298 AKT/NF-kappaB inhibitor xanthohumol targets cell growth and angiogenesis in hematologic malignancies.

Dell'Eva R, Ambrosini C, Vannini N, Piaggio G, Albini A, Ferrari N.

Cancer. 2007 Nov 1;110(9):2007-11.PMID: 17823911 Modulation of breast cancer cell survival by aromatase inhibiting hop (Humulus lupulus L.) flavonoids.

Monteiro R, Faria A, Azevedo I, Calhau C.

J Steroid Biochem Mol Biol. 2007 Jun-Jul;105(1-5):124-30. Epub 2007 Jul 23.PMID: 17643984 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard24.Protective effects of xanthohumol against the genotoxicity of benzo(a)pyrene (BaP), 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) and tert-butyl hydroperoxide (t-BOOH) in HepG2 human hepatoma cells.

Plazar J, Zegura B, Lah TT, Filipic M.

Mutat Res. 2007 Aug 15;632(1-2):1-8. Epub 2007 May 21.PMID: 17590382 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard25.Anticoccidial effects of xanthohumol.

Allen PC.

Avian Dis. 2007 Mar;51(1):21-6.PMID: 17461262 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard26.Angiogenesis and cancer prevention: a vision.

Noonan DM, Benelli R, Albini A.

Recent Results Cancer Res. 2007;174:219-24. Review.PMID: 17302199 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard27.Inhibition of S1P by polyphenols prevents inflammation and angiogenesis: NFkappaB, a downstream effector?

Soares R, Azevedo I.

Free Radic Biol Med. 2007 Jan 15;42(2):311. Epub 2006 Sep 29. No abstract available. PMID: 17189836 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard28.Distinct modulation of alkaline phosphatase isoenzymes by 17beta-estradiol and xanthohumol in breast cancer MCF-7 cells.

Guerreiro S, Monteiro R, Martins MJ, Calhau C, Azevedo I, Soares R.

Clin Biochem. 2007 Feb;40(3-4):268-73. Epub 2006 Oct 19.PMID: 17126313 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard29.Microbial metabolism of the prenylated chalcone xanthohumol.

Kim HJ, Lee IS.

J Nat Prod. 2006 Oct;69(10):1522-4.PMID: 17067177 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard30.Anti-proliferative properties of prenylated flavonoids from hops (Humulus lupulus L.) in human prostate cancer cell lines.

Delmulle L, Bellahcène A, Dhooge W, Comhaire F, Roelens F, Huvaere K, Heyerick A, Castronovo V, De Keukeleire D.

Phytomedicine. 2006 Nov;13(9-10):732-4. Epub 2006 May 5.PMID: 16678392 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard31.Influence of xanthohumol on the binding behavior of GABAA receptors and their lateral mobility at hippocampal neurons.

Meissner O, Häberlein H.

Planta Med. 2006 Jun;72(7):656-8. Epub 2006 Apr 24.PMID: 16636971 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard32.Effect of hop (Humulus lupulus L.) flavonoids on aromatase (estrogen synthase) activity.

Monteiro R, Becker H, Azevedo I, Calhau C.

J Agric Food Chem. 2006 Apr 19;54(8):2938-43.PMID: 16608212 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard33.Xanthohumol, a prenylflavonoid derived from hops induces apoptosis and inhibits NF-kappaB activation in prostate epithelial cells.

Colgate EC, Miranda CL, Stevens JF, Bray TM, Ho E.

Cancer Lett. 2007 Feb 8;246(1-2):201-9. Epub 2006 Mar 24.PMID: 16563612 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard34.Mechanisms of the antiangiogenic activity by the hop flavonoid xanthohumol: NF-kappaB and Akt as targets.

Albini A, Dell'Eva R, Vené R, Ferrari N, Buhler DR, Noonan DM, Fassina G.

FASEB J. 2006 Mar;20(3):527-9. Epub 2005 Dec 30.PMID: 16403733 [PubMed - indexed for MEDLINE]Related articlesFree articleItem in clipboard35.Xanthohumol kills B-chronic lymphocytic leukemia cells by an apoptotic mechanism.

Lust S, Vanhoecke B, Janssens A, Philippe J, Bracke M, Offner F.

Mol Nutr Food Res. 2005 Sep;49(9):844-50.PMID: 16144030 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard36.Xanthohumol, a new all-rounder?

Gerhäuser C, Frank N.

Mol Nutr Food Res. 2005 Sep;49(9):821-3. No abstract available. PMID: 16144029 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard37.Xanthohumol, the chalcone from beer hops (Humulus lupulus L.), is the ligand for farnesoid X receptor and ameliorates lipid and glucose metabolism in KK-A(y) mice.

Nozawa H.

Biochem Biophys Res Commun. 2005 Oct 28;336(3):754-61.PMID: 16140264 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard38.Xanthohumol isolated from Humulus lupulus Inhibits menadione-induced DNA damage through induction of quinone reductase.

Dietz BM, Kang YH, Liu G, Eggler AL, Yao P, Chadwick LR, Pauli GF, Farnsworth NR, Mesecar AD, van Breemen RB, Bolton JL.

Chem Res Toxicol. 2005 Aug;18(8):1296-305.PMID: 16097803 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard39.Broad spectrum anti-infective potential of xanthohumol from hop (Humulus lupulus L.) in comparison with activities of other hop constituents and xanthohumol metabolites.

Gerhäuser C.

Mol Nutr Food Res. 2005 Sep;49(9):827-31. Review.PMID: 16092071 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard40.A safety study of oral xanthohumol administration and its influence on fertility in Sprague Dawley rats.

Hussong R, Frank N, Knauft J, Ittrich C, Owen R, Becker H, Gerhäuser C.

Mol Nutr Food Res. 2005 Sep;49(9):861-7.PMID: 16092070 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard41.In vitro phase II metabolism of xanthohumol by human UDP-glucuronosyltransferases and sulfotransferases.

Ruefer CE, Gerhäuser C, Frank N, Becker H, Kulling SE.

Mol Nutr Food Res. 2005 Sep;49(9):851-6.PMID: 16092069 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard42.Xanthohumol does not affect the composition of rat intestinal microbiota.

Hanske L, Hussong R, Frank N, Gerhäuser C, Blaut M, Braune A.

Mol Nutr Food Res. 2005 Sep;49(9):868-73.PMID: 16092067 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard43.Xanthohumol induces apoptosis in cultured 40-16 human colon cancer cells by activation of the death receptor- and mitochondrial pathway.

Pan L, Becker H, Gerhäuser C.

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Vanhoecke B, Derycke L, Van Marck V, Depypere H, De Keukeleire D, Bracke M.

Int J Cancer. 2005 Dec 20;117(6):889-95.PMID: 15986430 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard45.Beer constituents as potential cancer chemopreventive agents.

Gerhäuser C.

Eur J Cancer. 2005 Sep;41(13):1941-54. Review.PMID: 15953717 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard46.In vitro antiplasmodial activity of prenylated chalcone derivatives of hops (Humulus lupulus) and their interaction with haemin.

Frölich S, Schubert C, Bienzle U, Jenett-Siems K.

J Antimicrob Chemother. 2005 Jun;55(6):883-7. Epub 2005 Apr 11.PMID: 15824094 [PubMed - indexed for MEDLINE]Related articlesFree articleItem in clipboard47.A safety study of oral tangeretin and xanthohumol administration to laboratory mice.

Vanhoecke BW, Delporte F, Van Braeckel E, Heyerick A, Depypere HT, Nuytinck M, De Keukeleire D, Bracke ME.

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Botta B, Vitali A, Menendez P, Misiti D, Delle Monache G.

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Goto K, Asai T, Hara S, Namatame I, Tomoda H, Ikemoto M, Oku N.

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Nikolic D, Li Y, Chadwick LR, Pauli GF, van Breemen RB.

J Mass Spectrom. 2005 Mar;40(3):289-99.PMID: 15712367 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard51.Xanthohumol, a novel anti-HIV-1 agent purified from Hops Humulus lupulus.

Wang Q, Ding ZH, Liu JK, Zheng YT.

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Avula B, Ganzera M, Warnick JE, Feltenstein MW, Sufka KJ, Khan IA.

J Chromatogr Sci. 2004 Aug;42(7):378-82.PMID: 15355578 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard53.Xanthohumol and related prenylflavonoids from hops and beer: to your good health!

Stevens JF, Page JE.

Phytochemistry. 2004 May;65(10):1317-30. Review.PMID: 15231405 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard54.The chalcone xanthohumol inhibits triglyceride and apolipoprotein B secretion in HepG2 cells.

Casaschi A, Maiyoh GK, Rubio BK, Li RW, Adeli K, Theriault AG.

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Nookandeh A, Frank N, Steiner F, Ellinger R, Schneider B, Gerhäuser C, Becker H.

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Buckwold VE, Wilson RJ, Nalca A, Beer BB, Voss TG, Turpin JA, Buckheit RW 3rd, Wei J, Wenzel-Mathers M, Walton EM, Smith RJ, Pallansch M, Ward P, Wells J, Chuvala L, Sloane S, Paulman R, Russell J, Hartman T, Ptak R.

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Herath W, Ferreira D, Khan SI, Khan IA.

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Stevens JF, Miranda CL, Frei B, Buhler DR.

Chem Res Toxicol. 2003 Oct;16(10):1277-86.PMID: 14565769 [PubMed - indexed for MEDLINE]Related articlesItem in clipboard59.Inhibitors of nitric oxide production from hops (Humulus lupulus L.).

Zhao F, Nozawa H, Daikonnya A, Kondo K, Kitanaka S.

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Rodriguez RJ, Miranda CL, Stevens JF, Deinzer ML, Buhler DR.

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Yilmazer M, Stevens JF, Buhler DR.

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Miranda CL, Yang YH, Henderson MC, Stevens JF, Santana-Rios G, Deinzer ML, Buhler DR.

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Miranda CL, Stevens JF, Ivanov V, McCall M, Frei B, Deinzer ML, Buhler DR.

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